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Fast Facts: Lymphoma
Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: ‧ a clear outline of the nature of lymphoma ‧ the essentials of clinical presentation, biopsy and histology ‧ a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques ‧ key aspects of staging and initial therapy ‧ clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype ‧ new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) ‧ a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: ‧ Epidemiology ‧ Cellular and molecular aspects ‧ Presentation, biopsy and diagnostic laboratory techniques ‧ Staging and general management principles ‧ Aggressive B-cell lymphomas ‧ Indolent B-cell lymphomas ‧ T-cell and natural-killer cell lymphomas ‧ Immunocompromised and HIV-positive patients ‧ Hodgkin lymphoma ‧ Treatment modalities ‧ Supportive care
- Cover
- Title Page
- Copyright
- Contents
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List of abbreviations
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Chemotherapy regimens
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- Introduction
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1. Epidemiology
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Incidence and relevant factors
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Risk factors
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Environmental causes of non-Hodgkin lymphoma
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Genetic causes of non-Hodgkin lymphoma
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2. Cellular and molecular aspects
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The role of lymphocytes in adaptive immunity
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Lymphocyte life cycle
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Normal lymph node architecture
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Origin of specific lymphoid disorders
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Molecular basis of cancer
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3. Presentation, biopsy and diagnostic laboratory techniques
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Clinical presentation
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Biopsy
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Basic histology
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Immunohistochemistry
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Flow cytometry and immunophenotyping
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Cytogenetics
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Fluorescent in-situ hybridization
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Molecular genetic techniques
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4. Staging and general management principles
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Nodal and extranodal lymphoma
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Management steps
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Staging
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Management principles
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Management of side effects
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Response to chemotherapy
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Relapse
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5. Aggressive B-cell lymphomas
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Diffuse large B-cell lymphoma
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Burkitt lymphoma
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Primary mediastinal (thymic) large B-cell lymphoma
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6. Indolent B-cell lymphomas
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Follicular lymphoma
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Mantle cell lymphoma
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Marginal zone lymphoma
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Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia
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Small lymphocytic lymphoma/chronic lymphocytic leukemia
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7. T-cell and natural killer cell lymphomas
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T-cell lymphoblastic leukemia/lymphoma
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Large granular lymphocytic leukemia
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Adult T-cell leukemia/lymphoma
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Peripheral T-cell lymphoma, unspecified
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Anaplastic large-cell lymphoma
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Angio-immunoblastic lymphoma
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Enteropathy-type T-cell lymphoma
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Natural killer cell (‘nasal’) lymphoma
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Mycosis fungoides and Sézary syndrome
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8. Immunocompromised and HIV-positive patients
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Post-transplant lymphomas
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HIV-associated lymphoma
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9. Hodgkin lymphoma
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Pathology
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Clinical presentation
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Management
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Prognosis
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10. Treatment modalities
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Chemotherapy
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Radiotherapy
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Immunotherapy
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High-dose therapy with stem-cell transplantation
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Small-molecule pathway inhibitors
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11. Supportive care
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Pain
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Nausea and vomiting
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Fatigue
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Bone marrow suppression
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Tumor lysis syndrome
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- Appendix: classification of non-Hodgkin lymphoma
- Useful resources
- Index
- 出版地 : 德國
- 語言 : 德文
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