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Fast Facts: Lymphoma

出版社
出版日期
2018/10/16
閱讀格式
EPUB
書籍分類
學科分類
ISBN
9781910797952

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Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: ‧ a clear outline of the nature of lymphoma ‧ the essentials of clinical presentation, biopsy and histology ‧ a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques ‧ key aspects of staging and initial therapy ‧ clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype ‧ new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) ‧ a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: ‧ Epidemiology ‧ Cellular and molecular aspects ‧ Presentation, biopsy and diagnostic laboratory techniques ‧ Staging and general management principles ‧ Aggressive B-cell lymphomas ‧ Indolent B-cell lymphomas ‧ T-cell and natural-killer cell lymphomas ‧ Immunocompromised and HIV-positive patients ‧ Hodgkin lymphoma ‧ Treatment modalities ‧ Supportive care
  • Cover
  • Title Page
  • Copyright
  • Contents
  • List of abbreviations
    • Chemotherapy regimens
  • Introduction
  • 1. Epidemiology
    • Incidence and relevant factors
    • Risk factors
    • Environmental causes of non-Hodgkin lymphoma
    • Genetic causes of non-Hodgkin lymphoma
  • 2. Cellular and molecular aspects
    • The role of lymphocytes in adaptive immunity
    • Lymphocyte life cycle
    • Normal lymph node architecture
    • Origin of specific lymphoid disorders
    • Molecular basis of cancer
  • 3. Presentation, biopsy and diagnostic laboratory techniques
    • Clinical presentation
    • Biopsy
    • Basic histology
    • Immunohistochemistry
    • Flow cytometry and immunophenotyping
    • Cytogenetics
    • Fluorescent in-situ hybridization
    • Molecular genetic techniques
  • 4. Staging and general management principles
    • Nodal and extranodal lymphoma
    • Management steps
    • Staging
    • Management principles
    • Management of side effects
    • Response to chemotherapy
    • Relapse
  • 5. Aggressive B-cell lymphomas
    • Diffuse large B-cell lymphoma
    • Burkitt lymphoma
    • Primary mediastinal (thymic) large B-cell lymphoma
  • 6. Indolent B-cell lymphomas
    • Follicular lymphoma
    • Mantle cell lymphoma
    • Marginal zone lymphoma
    • Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia
    • Small lymphocytic lymphoma/chronic lymphocytic leukemia
  • 7. T-cell and natural killer cell lymphomas
    • T-cell lymphoblastic leukemia/lymphoma
    • Large granular lymphocytic leukemia
    • Adult T-cell leukemia/lymphoma
    • Peripheral T-cell lymphoma, unspecified
    • Anaplastic large-cell lymphoma
    • Angio-immunoblastic lymphoma
    • Enteropathy-type T-cell lymphoma
    • Natural killer cell (‘nasal’) lymphoma
    • Mycosis fungoides and Sézary syndrome
  • 8. Immunocompromised and HIV-positive patients
    • Post-transplant lymphomas
    • HIV-associated lymphoma
  • 9. Hodgkin lymphoma
    • Pathology
    • Clinical presentation
    • Management
    • Prognosis
  • 10. Treatment modalities
    • Chemotherapy
    • Radiotherapy
    • Immunotherapy
    • High-dose therapy with stem-cell transplantation
    • Small-molecule pathway inhibitors
  • 11. Supportive care
    • Pain
    • Nausea and vomiting
    • Fatigue
    • Bone marrow suppression
    • Tumor lysis syndrome
  • Appendix: classification of non-Hodgkin lymphoma
  • Useful resources
  • Index
  • 出版地 德國
  • 語言 德文

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